On December 1, 2011, Rainbow Papaya from Hawaii will be fully approved for commercial shipments to Japan. This announcement marks the end of a long and tedious approval process which started in 1999, and the beginning of a new chapter for Hawaiian papaya growers. The approval of biotech papaya is significant because it is the first horticultural product, and the first direct-to-consumer food product to gain regulatory approval in Japan. The degree of acceptance of this product at the consumer level will serve as a leading indicator for numerous biotech products that are in the developmental and regulatory pipeline.