Researchers Make Migraine Breakthrough: Have You Ever Had a Migraine?

Living 2013/05/02 06:59:08
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A team of California researchers say they've discovered a genetic mutation that's linked to migraines. Senior investigator Louis J. Ptacek explained, "This is the first gene in which mutations have been shown to cause a very typical form of migraine. It’s our initial glimpse into a black box that we don’t yet understand."

Scientists studied the genes of two migraine-prone families and found that most of the family members who had migraines shared a particular mutation. They used lab tests to confirm that the mutation had biochemical effects, then tested it on mice. Then they got into things like "cortical spreading depression" and "astrocyte functioning," which you can read about here.

According to the study, migraines affect between 10 and 20 percent of the population, and most sufferers are women. The most common symptom of a migraine is severe headache, but they can also cause nausea, sensitivity to stimuli such as light or sound, and a strange aura.
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  • random.act5ofvi0let 2013/05/02 17:26:22
    And while the headache is the most painful element, I've always referred to it as a side effect. The disorientation, fatigue, nausea..generally bad feeling..thats the real meat and potatoes. They all come first, days in advance,and then..the recovery is the pain. A most horrific effect from the cause.

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  • jenmgabriel 2013/05/30 15:33:54
    I have had them so bad I lay on the floor in the bathroom cause I throw up and it is the worst feeling imaginable! My family has a history of Migraine's and it is very troubling with trips to the hospital and medication that turns you in to a Zombie! I had a migraine for 3 weeks once and had a doctor get upset cause he said it could cause brain damage if its not taken care of in time!
  • sglmom 2013/05/21 11:56:13
    YES ... I DO Suffer from Migraines ..
    the kind that can put you on the floor .. in constant pain ..
    nausea .. sensitivity to light/noise .. just awful to go through ..
    the only thing you can do is just turn EVERYTHING off .. and keep still ..
    and endure what is ...
  • Zella 2013/05/08 16:03:48
    when I was 10-13 I had migraines
  • SoLongFairLady 2013/05/07 05:47:04
    Yes, I feel one coming on, 12 hour night shifts can do that to you though.. Sad Panda :(
  • Gothic Angel 2013/05/07 03:30:31
    Gothic Angel
    Yes and a major concussion.I won't go into details but my then boyfriend and I got thrown into a classroom door.We are so lucky the jerk who threw us didn't kill us or crack our skulls.It hurt so bad like my head was in cased with 15 tons of concrete and throwing up every five mins.Most of the time I get normal headaches.
  • Nonpartisan 2013/05/07 02:51:57
    Yes and since I have been using the Gerson Therapy I hardly ever have them any more and if I do The Gerson Therapy will cure them in no time flat. Try it, it will Cure much more than just Headaches, it will improve your overall health. The Gerson Therapy has been very successfully curing Cancer, and many other degenerative conditions, since the start of World War Two.

  • dBrown 2013/05/06 13:49:23
    never, i don't know if this is normal.normal
  • jhoanne.key.1 2013/05/06 13:32:05
    Most of the time
  • Courtney Leigh 2013/05/06 12:20:11
    Courtney Leigh
    i get one everyday
  • ♩♪♥Victoria♥♪♫ 2013/05/06 11:32:28 (edited)
    Anyone who say's 'No' is obviously lying.....EVERYONE has had a headache before.

    What REALLY bugs me though, is the fact they tested it on animals.
  • Alex Go... ♩♪♥Vict... 2013/05/06 21:05:43
    Alex Goldsmith
    a migraine is a headache, but a headache is no migrane
  • Kezzi Morris 2013/05/06 10:41:50
    Kezzi Morris
  • Kat ♪ ~ ♪ 2013/05/06 10:41:07
    Kat ♪ ~ ♪
    Nasty things, went away on their own.
  • Alexander T Steward 2013/05/06 09:46:57
  • Veirah 2013/05/06 08:36:19
    Yes. I once got the sensation of a metal rod in my skull when I heard this girl repeatedly "Singing" the lyrics, "Baby, Baby, Baby, Ohhh!"
  • Yes
    MIZ®  ₱д₸Ɽ¡Ö₸ ₩дⱤⱤ¡ÖⱤ   †
    Actually. I don't know if this is what it is... but for about 3 years now I've had pain in my head from the moment I wake up 'til whenever I fall asleep- and as far as I know it's there 24/7. Don't know if this is migraine or what, neither does doc.
  • $mitty$r_1st 2013/05/06 05:47:43
    They are terrible. I would not wish them on anyone. They split your head, when you're just breathing. I had them when I was younger, up until I was about twenty. I would have to go to bad with them, sometimes for a day or two.Any movement hurt. Then when I was about twenty, I joined the Corps and went to Parris Island, and never had them since. I have never been able to figure that out. After thinking about it, it seems like it should have been Worse in boot camp.
  • liz 2013/05/06 02:18:52
    Coffee & a cool quite room fixes it
  • Zepland 2013/05/06 01:54:25
    Head and neck hurt, bad. And vomiting.
  • Freeranger 2013/05/06 01:45:19
    I have. They aren't any fun, so this could be good news.
  • CoinOperatedJoy 2013/05/06 01:44:55
    ughhhhh I get them twice a week, at the very least.
  • Civic M... CoinOpe... 2013/05/06 03:59:15
    Civic Minded
    Sorry to hear that this happens so often to you.
  • CoinOpe... Civic M... 2013/05/06 15:43:31 (edited)
    Thanks hun :o) I'm a walking nightmare! lol There is far too much wrong with me, but migraines are certainly top of the list.

    I haven't been able to find a preventative migraine med yet, but Midrin (sp?) is pretty good for relief once it comes on. As soon as you feel it creeping, pop 2 red pills. lmao My son is on a preventative med the Midrin as well.

    My 10 & 4 year olds complain about headaches from time to time, but nothing like Michel or I used to get, starting from early childhood.
  • Civic M... CoinOpe... 2013/05/06 17:51:06
    Civic Minded
    You would think by now that migraines would be a non-issue. I have become suspicious of pharmaceutical companies' motives. I don't think that they intend to cure anything.

    I haven't seen the whole thing yet, but I was watching Pink Ribbons Inc on netflix last night. I have an issue with some of the interviewees' attitudes about capitalism, but the point is well taken that with the BILLIONS of $$$$ raised to fund a "cure" for breast cancer, there is none really. The people who participate in the fundraising ploys need hope and come away empty handed.

    I admit that I am still harboring feelings of deep dissatisfaction that CCFA hasn't made a significant contribution to helping people live a healthy life after a diagnosis of Crohn's Disease. I stopped giving them money when my son died.

    Ahhh! Enough venting! You have a much better attitude than I! You are awesome!
  • CoinOpe... Civic M... 2013/05/07 03:55:45
    Why, thank ya! I'm quite fond of you, as well. :o)

    I believe there are cures for pretty much anything that ails ya, but there's no money in the cure. The money is in the treatment. Cancer, AIDs, MS, Fibromyalgia, other chronic illness' are really expensive. They nickle and dime you nearly to death themselves. Drives me nuts!
  • Civic M... CoinOpe... 2013/05/07 04:31:22
    Civic Minded
    I do have a lot of holistic info on natural treatments. The AMA and pharmaceutical companies work in conjunction with the FDA to interfere with our choices. You are right. It's about $$$
  • CoinOpe... Civic M... 2013/05/07 04:36:58
    Everything is about $$$! LOL It's pathetic!
  • ☆ElenaDiamond☆ 2013/05/06 01:42:41
    I used to have them a lot. I haven't had one in years. :)
  • Sunny ~Jiraiya sama~ 2013/05/06 00:38:02
    Sunny ~Jiraiya sama~
    Yes, it's unbearable the last time I didn't take a pill it lasted for several hours
  • <3 :D live fast, die young 2013/05/05 23:59:05
    <3 :D  live fast, die young
    who doesn't??
  • Wolfie <3 :D ... 2013/05/07 00:00:16
    You apparently...DO NOT...If you have EVER had an "actual" "migraine".....YOU WOULD KNOW THE DIFFERENCE AND YOU WOULD NEVER SAY SOMETHING LIKE "who doesn't" !!!!!!!
  • <3 :D ... Wolfie 2013/06/24 04:26:49
    <3 :D  live fast, die young
    that's mean u don't have to make a big deal out of it dude watch yourself
  • Ketel-One 2013/05/05 22:49:06
    My brother gets them pretty bad though
  • cloud strife 2013/05/05 22:08:24
    cloud strife
    From my.class
  • SlaveWaterNymph 2013/05/05 21:06:08
    ive been having them since i was young. So does that mean most of us are mutated? hm i dont think so.
  • Joe Windham 2013/05/05 20:28:43
    Joe Windham
    Once or twice, I think
  • ShinyUmbreon01 2013/05/05 19:26:16
  • jeane 2013/05/05 18:49:16 (edited)
    Frequently - on prescription meds. Unfortunately passed them on to one of my children. He has them only intermittently though.
  • CoinOpe... jeane 2013/05/06 01:47:43
    Ugh, I feel for ya. I get them weekly and have passed it on to 1 child for sure. The other 2 get headaches, but I haven't seen the full effect yet, so I'm not sure. :/
  • jeane CoinOpe... 2013/05/06 01:50:49
    I am just thankful for the new meds to help control them. It could be worse.

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