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Do "White" People Get Sickle Cell Anemia? Another Race Myth Solved!

Captain Foxhound BN0 2011/05/10 23:03:17


Yes, people who are "White" can carry sickle cell trait. Sickle cell diseases are actually a broad group of hemoglobinopathies
(genetic blood disorders) that affect over 250 million people around
the world, including people in Africa, North & South America, the
Mediterranean and Middle East, South Asia, and Europe.


Sickle cell trait is not a disease or illness - it is merely a
descriptive term that indicates a person has inherited on "normal"
hemoglobin gene (Hb A) and another "abnormal" hemoglobin gene (Hb S).
Some individuals with sickle cell trait are at increased risk for sudden
death if they are dehydrated or exposed to high altitudes, but this
occurs rarely.


If two individuals who have sickle cell trait (Hb AS) mate, then there is a 25% chance with each birth
that they will have a child with sickle cell anemia (Hb SS); a 25%
chance that they will have a child with normal hemoglobin (Hb AA); and a
50% chance that they will have a child with sickle cell trait.


Sickle cell trait occurs in approximately 1 in 12 African Americans; 1 in 1400 Hispanics, and nearly 1 in 100,000 Whites.


Read more: http://wiki.answers.com/Q/Do_white_people_carry_sickle_cell_T...

http://www.pbs.org/race/000_About/002_04-teachers-04.htm

http://www.netwellness.org/healthtopics/sicklecell/sicklecell...

http://aablooddriveandmarrowregistry4sicklecellawareness.webs...

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Top Opinion

  • Disko Pickle 2011/05/11 05:18:06
    Disko Pickle
    +21
    People with sickle-cell anemia are immune to malaria, one of the most deadly diseases in the world. Having sickle-cell actually gives you an adaptive survival advantage over most of the rest of the world population.

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Opinions

  • Jackie 2015/03/10 13:29:01
    Jackie
    +1
    I didn't know this.
  • Whodini 2015/03/10 00:28:05
    Whodini
    +1
    And men get breast cancer
  • Rodney 2015/03/09 23:35:13
    Rodney
    +1
    More importantly is that Malaria leads Sickle Cell. Sickle Cell is rare in South Africa while Malaria risks are higher. However, a person who is bit by a malaria carrying mosquito gets the cell that mutates the blood cells to Sickle Cell. That mutation is then passed on through offspring. Should, as this post says, mate with another person carrying the mutated gene, you get the greater chance of contracting Sickle Cell. So... Sickle Cell is not a race based genetic disease, it is an area or nationality disease. Greece has higher rates of Sickle Cell then does South Africa, for instance.
  • Sarah 2015/03/09 23:01:28
    Sarah
    +1
    Yes white can have sickle cell anemian
  • Trey 2015/03/01 21:03:33
    Trey
    +3
    Yes. Due to my genetics, I had to get tested for Sickle Cell, as a baby. My grandfather came to the United States from Cyprus in the Mediterranean.
  • Stacey Smith 2014/07/01 21:22:04
    Stacey Smith
    +5
    I think we are all thinking of race very differently now because of genetics. I recently found out that my great-great grandmother was blackfoot Cherokee which is a misnomer for a mix of black and Cherokee in the south. I'm as white as a bed sheet in appearance. I'm waiting to find out what kind of anemia I have and hopefully I don't have sickle cell, but there is the possibility for sure, particularly with it being more common with African Americans and having that ethnicity in my ancestry. Maybe genetics will humble people of all races and keep them from judging every book by it's cover! The study of genetics is so very fascinating.
  • This is W³ 2013/07/15 17:41:30
    This is W³
    +1
    I was not aware of this. Thank you for bringing this to everyone's attention.
  • cindy.b.hill.1 2012/08/30 02:05:51
    cindy.b.hill.1
    +3
    http://Facebook.com/groups/Pr...


    Xooma Sickle Cell Transformation

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  • Betty 2011/09/23 03:18:28
    Betty
    +2
    My son is white and has been diagnosed with advanced sickle cell anemia. I am very confused. I am just searching for answers. He is 22 and this has just surfaced. We are desperate for answers but everybody seems to have different inputs. No facts. I need answers such as how and where did he get it. He is have a blood transfusion on the 30th of September. Is this going to really help or put him in more pain. He is the father of two little girls. Shouldn't they be tested?
  • Captain... Betty 2011/10/01 23:35:50
    Captain Foxhound BN0
    +1
    It is hereditary and came from one or both of his parents and I assume his children should be tested.
  • brea Betty 2011/10/11 10:10:42
    brea
    +3
    sir Sickle cell anemia is geneticly given to someone you cant just catch it from someone. and Sickle cell will not kill him its not like its cancer. and a blood transfusion sounds kind of off. I mean it wont hurt him I guess it should make him feel better but if he is in sickle cell crisis water and medicine will make him feel 10x better than an tranfusion depending on the problem. I am 16 and Ive had Sickle cell my hole life and it does not give you a time line on how long you are going to live. if you research it then you will see that its a very common disease
  • sara je... Betty 2014/03/11 00:35:49
    sara jennings
    +1
    Betty you have to have African or Mediterranean heritage in order to get this disease Since he's just being diagnosed he shoud see a specialists and learn more. A blood transfusion helps alot it pursuit hemoglobin counts up.txt his daughters should be tested
  • angelic... Betty 2014/08/19 20:12:23
    angelica owens
    +3
    Well if he has it, this means you and his father is a carrier. Which means you two only have the trait. So he should get his kids tested, they may be carriers also. If they partner up with someone else who has trait when they are older. Its possible for their kids to get the full disease. I'm a carrier, so are my kids.its very important to educate them on sickle cell. Very painful disease to have. My prayers go out to your son.
  • Darnel 2011/05/13 17:13:47
    Darnel
    +1
    Sigh.
    Pluses and Minuses.
  • Myrle Hulme 2011/05/12 07:12:39
    Myrle Hulme
    White people can carry the trait but not sickle cell anemia, it is basically prevalent in people and decendants from sub-saharian Africa
  • Warren ... Myrle H... 2011/05/14 14:36:02
    Warren - Novus Ordo Seclorum
    +3
    No, the trait means that a person carries one recessive gene. Someone who carries two recessive genes will have anemia. Two people, each with sickle cell trait will produce 25% offspring with anemia. This is mathematically true regardless of race or ethnic background.
  • Myrle H... Warren ... 2011/05/16 06:14:45
    Myrle Hulme
    +1
    I will bow to your knowledge.
  • Warren ... Myrle H... 2011/05/16 19:11:49
    Warren - Novus Ordo Seclorum
    +1
    My daughter carries the sickle cell trait gene and she is as white as they come.
  • Myrle H... Warren ... 2011/05/17 08:40:39
    Myrle Hulme
    I am very sorry to hear this as, if my knowledge is correct, not cureable and they normally die young. I sincerely hope this does not happen to your daughter
  • mia.sco... Myrle H... 2012/09/26 18:03:35
    mia.scott.587
    +5
    Ugh, they do not die young especially if carrying the trait. Just stop. You are embarrassing yourself lady.
  • SickleS... Myrle H... 2014/07/12 00:56:04 (edited)
    SickleSoldier
    +3
    Some people say the darndest things! Spread facts not ignorance!
  • mia.sco... Myrle H... 2012/09/26 18:02:06
    mia.scott.587
    +3
    Negative. Whites can have sickle cell anemia and it's also carried by Asians, middle Eastern descent, Africans, latinos, and Mediterranean descent. So you see just not sub-saharian Africans carry this. Do more research please. Don't continue to look like an ass.
  • Ken 2011/05/12 03:47:40
    Ken
    +2
    The sickle cell anemia gene is an adaptation to malaria. Those with one of the genes are malaria resistant, those with two of the genes die. Now if you die before having children, your genes die with you. But the gene survives in those areas where malaria is endemic, because it increases the survival of 3/4s of the young. This is not a black white issue ....it is a tropical vs. temperate zone issue. This specific adaptation to malaria appears to have emerged in Africa making African Americans much more likely to survive a malaria epidemic than pure Europeans.

    A side effect of this advantage is that 1 in 4 children of those whose parents have this resistance to malaria, get sickle cell anemia and die before they have children....but 3 of the 4 children survive malaria.
  • Captain... Ken 2011/05/12 05:08:28
    Captain Foxhound BN0
    +1
    Basically it's not an advantage without lots of malaria around.
  • Ken Captain... 2011/05/12 16:55:18
    Ken
    +1
    The sickle cell gene is a disadvantage when malaria is not endemic because it kills 1 of 4 children. But where malaria is rampant, it saves 3 of 4 children. The emergence of modern medicine and mosquito control has reduced or eliminated the value of this gene making it a liability for those populations which carry it.
  • boo Ken 2011/05/14 16:28:06
    boo
    It is NOT an adaptation to malaria.
  • Ken boo 2011/05/14 17:50:41
    Ken
    +3
    Okay...I made an assertion without identifying sources. Here are a few references:
    "Scientists believe that sickle cell disease originated thousands of years ago as a hemoglobin gene mutation where malaria is a common illness." Read more: Malaria & Sickle Cell Disease | eHow.com http://www.ehow.com/facts_514...

    "Sickling and sickle cell disease also confer some resistance to malaria parasitization of red blood cells, so that individuals with sickle-cell trait (heterozygotes) have a selective advantage in some environments." http://en.wikipedia.org/wiki/...

    "Sickle-cell hemoglobin may gas malaria into submission, a new study proposes. People who carry a mutation that deforms the oxygen-carrying protein in red blood cells are well-known to be protected against malaria." http://www.usnews.com/science...

    There are many additional references but this seems to be adequate to support my assertion.
  • boo Ken 2011/05/14 17:52:34
    boo
    I'm happy you said "your" assertion :-)
  • Ken boo 2011/05/14 18:47:10
    Ken
    My assertion is the assertion of modern science and proven through controlled experiments. In other words, better demonstrated than the theory that chemo therapy cures cancer. Of course there is no reason for you to believe modern science. You may as well continue to think the earth is flat and at the center of the universe.

    And don't give me that BS about you believe the Bible because in Genesis God created the sun and the moon on day 4. So clearly days 1 - 3 were not solar days and therefore were of indefinite duration...and if days 1 - 3 were not solar days, than arguing that days 4 through 7 were solar days if preposterous and assumes a schizophrenic God who changes willy nilly. Of course, if God is so irrational, God may have created all this evidence just to deceive humanity but I refuse to accept a deceptive God...and think you should reject such a stupid idea as well.

    Is this clear enough? You are using religion as an excuse not to use your brain and to reject what others have discovered. I believe you embarrass God.
  • boo Ken 2011/05/14 19:12:10
    boo
    Wow ... you're scientifically paranoid. I'm not religious :-)
  • Ken boo 2011/05/14 19:51:09
    Ken
    +1
    My point....

    You have made an assertion without supporting evidence. I provided supporting evidence and you then question it as "my assertion" Such behaviors are encountered in children and dogmatic religious zealots. I assumed you were an adult. Sorry.
  • boo Ken 2011/05/15 13:33:09
    boo
    I am an adult ... just not a crazy one :-)
  • Ken boo 2011/05/15 15:41:23 (edited)
    Ken
    +3
    Okay ... so if the sickle cell trait is not an adaptation to malaria, why do you think it is common among people from areas where malaria is endemic?

    Don't keep us guessing. You have already said it is not an adaptation to malaria so you must have a better explanation.
  • Ken boo 2015/03/15 03:45:18 (edited)
    Ken
    I am still guessing about why you think the sickle cell trait is not an adaptation to malaria. Unless i get an answer soon, I must assume you have no facts to support your opinion.

    Only a child or a religious zealot would assume the world is as the imagine it, rather than as they observe it.
  • mia.sco... Ken 2012/09/26 18:05:44
    mia.scott.587
    +2
    Sir, I know several Africans and Malaria can be caught if you have sickle cell and only worsens the condition. Scientific controlled experiments bs.
  • Ken mia.sco... 2012/09/27 01:50:11
    Ken
    +1
    I am not a doctor nor a geneticist so all I know is what I have been told. Here are a few sources which lead me to believe research has led doctors and geneticists believe the recessive sickle cell helps the person carrying the trait resists malaria.
    http://sickle.bwh.harvard.edu...
    http://en.wikipedia.org/wiki/...
    http://www.buzzle.com/article...
    http://fox6now.com/2012/09/24...
    http://www.cdc.gov/malaria/ab...

    I could go on with the list but you can quickly develop it yourself by entering a search engine query for sickle cell anemia and malaria. If you are a physician or geneticist, you probably have access to even better information sources and are better qualified than I to reach the correct conclusions about these articles.

    Your anecdotal examples, however, are of no use to me. As I understand the impact, the sickle cell trait does not prevent malaria but it does help the patient survive malaria. To my knowledge science does not yet understand the chemical pathway which provides this resistance.
    I am not a doctor nor a geneticist so all I know is what I have been told. Here are a few sources which lead me to believe research has led doctors and geneticists believe the recessive sickle cell helps the person carrying the trait resists malaria.
    http://sickle.bwh.harvard.edu...
    http://en.wikipedia.org/wiki/...
    http://www.buzzle.com/article...
    http://fox6now.com/2012/09/24...
    http://www.cdc.gov/malaria/ab...

    I could go on with the list but you can quickly develop it yourself by entering a search engine query for sickle cell anemia and malaria. If you are a physician or geneticist, you probably have access to even better information sources and are better qualified than I to reach the correct conclusions about these articles.

    Your anecdotal examples, however, are of no use to me. As I understand the impact, the sickle cell trait does not prevent malaria but it does help the patient survive malaria. To my knowledge science does not yet understand the chemical pathway which provides this resistance.
    (more)
  • mia.sco... Ken 2012/09/27 23:23:08
    mia.scott.587
    +2
    I have sickle cell. So I am speaking from life and from others that live with the disorder. I need no search engine to tell me other wise or scientist.
  • Ken mia.sco... 2012/09/28 03:04:06
    Ken
    You are of course free to believe whatever you wish. I am not inclined to accept your anecdotal examples, however, over carefully constructed studies. I also recognize there are many examples of scientific follies in the past. This may be another such folly.
  • daitchi... Ken 2014/03/18 08:49:52
    daitchie ponthieux
    +3
    Lol I like reading these post....man you all are being ignorant....malaria is resistant in sickle cell people....my daughter in law has it and beat it...you gain more evidence by experience than reading and seeing what quacky scientist have to say....I don't believe a word any scientist has to say....the world was going to end for the Milan calendar ended....did it ever occur to any of the so called smartest person in the world to think the Milan calender ended because there was no one left to keep the calendar going....I don't believe in science...science is based on theories and not facts...excuse me theories until proven as facts....science theories god Jesus fact....I'm not a religious finatic....but I know my lord and if you were to take a little time from your day of gossiping....and read your bible....pray get to know god....Jesus Christ....you would know...Jesus is true god...its something you just know.....Lola I love my Lord Jesus.....
  • Ken daitchi... 2014/03/18 13:01:35
    Ken
    +1
    You are of course free to believe as you wish. The Bible can be a source for moral guidance but it is not going to tell a doctor how to treat your malaria or most other diseases. Similarly it can provide insight into how to manage a team building a computer but will not tell the engineer how to design an integrated circuit.

    So while you may not believe in science, you and I would not be communicating if someone didn't accept science long enough to build the computers and the network we are using to communicate.

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